the first songbird
basal ganglia
connectome

Render by Konstantinos Alexandrou

about

Here, we introduce the first vertebrate basal ganglia connectome, comprising over 8,500 automated neuron reconstructions connected by about 20 million synapses. The basal ganglia are a key brain structure for many neural disorders, ranging from Parkinson's disease to psychiatric conditions. We hope that our connectome can contribute to a fundamental understanding of basal ganglia function. The data were obtained from a zebra finch, a vocal learner and model organism for human speech. Electron microscopy image quality and automated reconstruction quality allowed for analysis with minimal manual proofreading.

Fly-through of 3D reconstruction of the dataset. The dataset spans a volume of 256 x 256 x 384 μm3 with a voxel size of 10 x 10 x 25 nm3. Link to full fly-through.

Video by Konstantinos Alexandrou, meshes by Alexandra Rother

THE HEADLINES

~8,500 automated
neuron reconstructions

~20 million synapses

16 cell types

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the publications
connectivity data
cell types
code
interactive analysis
raw data